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| Name | Risk factors of AECOPD with depression and/or anxiety symptoms - Video abstract [ID 245842] |
| Video Uploader | Video From Dove Medical Press |
| Upload Date | This Video Uploaded At 19-06-2020 02:04:35 |
| Video Discription | Video abstract of an original research "Multiple factors analysis of depression and/or anxiety in patients with acute exacerbation chronic obstructive pulmonary disease” published in the open access International Journal of Chronic Obstructive Pulmonary Disease by Jian Long, Yao Ouyang, Haizhen Duan et al. Objective: To reveal the risk factors, the symptom distribution characteristics, the clinical values of white blood cell counts (WBC counts), red blood cell distribution width (RDW), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and monocyte-tolymphocyte ratio (MLR) in hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) combined with depression and/or anxiety. Methods: The study included prospective cross-sectional and case–control studies, and was executed in the Affiliated Hospital of Zunyi Medical University, Guizhou, China. Previously diagnosed chronic obstructive pulmonary disease (COPD) patients who admitted to the hospital with AECOPD, patients with depression and/or anxiety, and healthy people were enrolled in the study. The Hamilton Rating Scales were used to assess all subjects, and the complete blood counts (CBC) were collected. Baseline data and clinical measurement data [spirometry, arterial blood gas analysis, and COPD evaluation test (the CAT scale)] from patients with AECOPD were collected. Results: Of the 307 patients with AECOPD included, 63.5% (N=195) had depressive and/or anxiety symptoms, and 36.5% (N=112) had no symptoms. Sex, respiratory failure, number of comorbidities, number of acute exacerbations in the previous year and the CAT score were closely related to AECOPD combined with depression and/or anxiety (p<0.05). The CAT scale score were the independent risk factor (OR=6.576, 95% CI 3.812–11.342) and significant predictor of AECOPD with depression and/or anxiety (AUC=0.790,95% CI 0.740–- 0.834); the patients with depression and/or anxiety were more severe and characteristic than the patients with AECOPD combined with depression and/or anxiety; RDW was associated with AECOPD with depression and/or anxiety (p=0.020, OR1.212,95% CI1.03–1.426), and had certain clinical diagnostic value (AUC=0.570,95% CI 0.531–0.626). Conclusion: Depression and anxiety should not be ignored in patients with AECOPD. The severity and quality of life of COPD were closely related to the occurrence of depression and/or anxiety symptoms. In most cases, perhaps depression and anxiety in AECOPD are only symptoms and not to the extents of the diseases. RDW had clinical diagnostic value in AECOPD combined with depression and/or anxiety. NLR, PLR, MLR, and RDW may become the novel indicators for evaluating the degree of inflammation of AECOPD and deserve further research. Read the full paper herehttps://www.dovepress.com/multiple-factor-analysis-of-depression-andor-anxiety-in-patients-with--peer-reviewed-article-COPD |
| Category | Science & Technology |
| Tags | Dove Medical Press | Dovepress | Long | Affiliated Hospital of Zunyi Medical University | International Journal of Chronic Obstructive Pulmonary Disease | Anxiety | Depression | AECOPD | Comorbidity | Hamilton scale | Inflammatory markers |
