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| Name | Cyanide Poisoning - HCN: a deadly poison | Biology revision video - GCSE A Level University |
| Video Uploader | Video From DrugsPlus |
| Upload Date | This Video Uploaded At 06-01-2021 09:34:18 |
| Video Discription | A brief description of what happens shortly after cyanide poisoning! A cyanide is a chemical compound that contains a carbon atom and a nitrogen atom, covalently bound by a triple bond. The most common form of this is hydrocyanic acid, or hydrogen cyanide. Although cyanide is often used intentionally for murder, it is also found in certain plants, as well as the seeds of apricots, apples and peaches. Some of the most famous uses of cyanide poisoning include the murders of World War 2 hero Alan Turing, and confidant of the final Russian tsar, Rasputin. Tragically, cyanide was also used in the gas chambers of Nazi concentration camps. Once cyanide is ingested or inhaled, it enters the bloodstream and acts on mitochondria – more specifically the enzyme cytochrome C oxidase, on inner mitochondrial membranes. This enzyme is part of the electron transport chain, and uses electrons from corresponding enzymes to form molecular oxygen. In doing this, ATP is generated, and aerobic respiration is complete – a vital process for all living cells. During cyanide poisoning however, cyanide molecules bind to iron atoms in cytochrome c oxidase, which prevents it from transferring the electrons to oxygen. This means that aerobic respiration cannot occur, and ATP cannot be generated. This causes a condition known as histotoxic hypoxia – cells of an organism are unable to generate ATP, despite normal physiological delivery of oxygen via the bloodstream. This particularly affects organs which depend highly on aerobic respiration, such as the heart, and the central nervous system. This quickly causes seizures, apnea (the cessation of breathing), and cardiac arrest – which is soon shortly by death. Chronic low-dose exposure also causes problems however – in tropical Africa Cassava roots are a primary food source. If these are improperly processed before consumption, they can contain low levels of cyanide. This chronic exposure causes paralysis, hypothyroidism and even miscarriages – and is a huge problem in countries such as Uganda. Subscribe to DrugsPlus: http://www.youtube.com/channel/UCM1t1_O-juX91x9XhczZISg?sub_confirmation=1 Knock your GCSE, A level or university exam results out of the park with DrugsPlus. With videos on physiology, disease and drugs, this is your number one stop for anything involving medical health. Topics covered range from the heart, to the brain; from the reproductive system, to the endocrine system; from cyanide, to COVID-19. People who enjoy DrugsPlus include everyone from prospective medical students, to anyone with a general interest in drugs and disease. DrugsPlus solely exists for educational purposes and should not be used for personal medical advice, nor as an aid to self-diagnosis – always consult with your physician or healthcare professional. |
| Category | Education |
| Tags | cyanide | poison | poisoning | cyanide poisoning | concentration camp | gas chamber | Alan Turing | Rasputin | HCN | CN- | histotoxic hypoxia | cassava |
