Isaac Best Run

1:00:21

BEST RUN OF 2022? (So far) - The Binding Of Isaac: Repentance #357
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The Luckiest Isaac Run Possible?
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The New New Most POWERFUL RUN In Isaac?? - The Binding Of Isaac: Repentance Ep. 833
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5 Brimstones, 1 Run
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56:34

STRONGEST LOST RUN EVER - The Binding Of Isaac: Repentance Ep. 619
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STRONGEST RUN OF THE YEAR - The Binding Of Isaac: Repentance Ep. 580
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The Actual Strongest Run Ever? | Repentance on Stream (Episode 165)
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RUN OF THE YEAR! - The Binding Of Isaac: Repentance Ep. 723
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I Got The BEST Angel Run EVER
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The Luckiest Run In Isaac History?
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Every (Original Run) Episode of Futurama Reviewed!
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45:23

Best Run Ever | The Binding of Isaac: Rebirth
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This Is What A 19 Hour Isaac Run Looks Like...
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14:43

The BEST Azazel Synergy
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1:04:49

MOST POWERFUL RUN OF THE YEAR! - The Binding Of Isaac: Repentance Ep. 908
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THE MOST POWERFUL RUN IN ISAAC - The Binding Of Isaac: Afterbirth+ #853
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2:30

Worlds FASTEST Isaac Repentance Run [WR] [Random Seed]
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1:01:52

The new new new new new new STRONGEST RUN of the year! - The Binding Of Isaac: Repentance - #1142
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14:31

The 1 In 1,000,000 Start:
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