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| Name | Long-Term Synaptic Depression Triggered by Microglia |
| Video Uploader | Video From Cell Press |
| Upload Date | This Video Uploaded At 02-04-2014 15:40:20 |
| Video Discription | Zhang et al. discovered that microglial cells sense inflammatory stimuli and hypoxia in the brain via complement receptor 3 and produce reactive oxygen species (ROS) by NADPH oxidase. The diffusion of ROS into neurons triggers long-term depression of synaptic transmission, showing a new mechanism through which microglia rapidly reduce synaptic transmission. For more information, see Zhang et al., Neuron 82(1). |
| Category | Science & Technology |
| Tags | Microglia | synaptic transmission | long term depression | neuroinflammation | NADPH oxidase | Neuron |
