Video Discription |
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I discuss the new hydrogen sulfide SIBO test, symptoms, and treatment. I also discuss my experience with hydrogen sulfide SIBO and the latest thinking on this subject from SIBO experts including Dr. Mark Pimentel, Dr. Allison Siebecker, and Dr. Nirala Jacobi. I also talk about the new classification of methane SIBO as IMO (intestinal methanogen overgrowth).
Videos referenced/relevant videos:
https://www.youtube.com/watch?v=WFfl0WnHpI8&t=48s
https://www.youtube.com/watch?v=EtMfuKUfdcg&t=44s
References:
1. Pimentel, M., Saad, R. J., Long, M. D., & Rao, S. S. (2020). ACG clinical guideline: small intestinal bacterial overgrowth. American Journal of Gastroenterology, 115(2), 165-178.
https://journals.lww.com/ajg/fulltext/2020/02000/acg_clinical_guideline__small_intestinal_bacterial.9.aspx
2. Singer-Englar, T., Rezaie, A., Gupta, K., Pichetshote, N., Sedighi, R., Lin, E., ... & Pimentel, M. (2018). Competitive hydrogen gas utilization by methane-and hydrogen sulfide-producing microorganisms and associated symptoms: results of a novel 4-gas breath test machine. Gastroenterology, 154, S-47.
3. https://www.drkarafitzgerald.com/2020/10/01/dr-mark-pimentel-presents-new-perspectives-on-sibo-and-ibs/
4. https://www.youtube.com/watch?v=Qn8FvYEuFlM
5. https://ndnr.com/gastrointestinal/hydrogen-sulfide-dysbiosis-a-case-study/
6. Leite, G., Morales, W., Weitsman, S., Celly, S., Parodi, G., Mathur, R., ... & Pimentel, M. (2020). The duodenal microbiome is altered in small intestinal bacterial overgrowth. PloS one, 15(7), e0234906. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234906
7. Leite, G. G., Weitsman, S., Parodi, G., Celly, S., Sedighi, R., Sanchez, M., ... & Lo, S. K. (2020). Mapping the Segmental Microbiomes in the Human Small Bowel in Comparison with Stool: A REIMAGINE Study. Digestive Diseases and Sciences, 1-10.
https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=mapping+the+segmental+microbiomes+pimentel&btnG=
8. Fowler, H., Pichetshote, N., Hosseini, A., Takakura, W. R., Sedighi, R., Chang, C., ... & Rezaie, A. (2020). Su1211 THE FIRST STUDY TO DETERMINE THE NORMAL RANGE OF EXHALED HYDROGEN SULFIDE (H2S) USING A NOVEL 4-GAS BREATH TEST DEVICE IN HEALTHY SUBJECTS. Gastroenterology, 158(6), S-545.
0:00 Intro
32:03 SIBO basics
1:18 IMO (intestinal methanogen overgrowth)
2:55 Hydrogen sulfide SIBO testing
4:53 Outdated markers for hydrogen sulfide SIBO
8:28 Host response
9:54 Symptoms
11:34 Bacteria implicated?
13:35 Treatment
14:24 Xifaxan and NAC?!
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