Penicillin: From Fleming to the Pharmacy

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Name	Penicillin: From Fleming to the Pharmacy
Video Uploader	Video From Patrick Kelly
Upload Date	This Video Uploaded At 26-09-2023 13:01:45
Video Discription	Penicillin's discovery by Alexander Fleming in 1929 gets a lot of hype as the advent of antibiotics. But in reality, Fleming was just one part of the story. A team from Oxford University led by Howard Florey, in partnership with the Northern Lab in the USA brought penicillin production to the world. In this video, Patrick Kelly tells the history of penicillin. ☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️ 🔗 L I N K S 🔗 📱Instagram: https://www.instagram.com/patkellyteaches/ 🐦Twitter: https://twitter.com/PatKellyTeaches 💰Patreon: https://www.patreon.com/corporis 🔬Main channel: www.youtube.com/corporis/ 📚My favorite books https://docs.google.com/document/d/1wuG-8EiF2lMbFdEG-9k1qi1d1KZAdGK1o41o7SYed_k/edit?usp=sharing 🔑 P A T R O N S 🔑 Ron Blumenfeld Joanne K Sal F. Ansel K Anton Brandon K Rourou Y Brendan P Dane M Kristoffer R Jakub V Joe B Karly N Mindi F Kathy K Hyeon-Seo Jacob S. Robin B Sarah B Carl Karen S Michael R Brian H Brian T Waffles the Dog Silverstar Robb W Brian B Michael G 📜 S O U R C E S 📜 Image attributions and fact checked script can be found here. You do not need to be a Patron to view: https://www.patreon.com/posts/penicillin-89784054 Miracle Cure, the Creation of Antibiotics https://www.amazon.com/Miracle-Cure-Creation-Antibiotics-Medicine/dp/0525428100?&_encoding=UTF8&tag=corporis-20&linkCode=ur2&linkId=536c2608b02b02e77356edd136b4d016&camp=1789&creative=9325 Science, Government, and the Mass Production of Penicillin by PETER NEUSHUL (1993) https://www.jstor.org/stable/24623264 The Discovery of Penicillin: New Insights After More Than 75 Years of Clinical Use (2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403050/ Post- penicillin antibiotics https://www.researchgate.net/publication/32886496_Post_penicillin_antibiotics_from_acceptance_to_resistance Fleming biographies https://www.aai.org/About/History/Notable-Members/Nobel-Laureates/AlexanderFleming https://sciencehistory.org/education/scientific-biographies/alexander-fleming/ https://www.pbs.org/wgbh/aso/databank/entries/bmflem.html https://www.scientificamerican.com/article/penicillin-wasn-rsquo-t-alexander-fleming-rsquo-s-first-major-discovery/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520913/ Fleming’s 1917 Flavine paper https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(01)52126-1/fulltext Fleming’s WW1 notebook clippings https://www.bl.uk/collection-items/alexander-flemings-notebook-june-1917-1918 Fleming’s 1929 Penicillin paper https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048009/pdf/brjexppathol00255-0037.pdf Fleming’s 1932 Lysozyme retrospective in Journal of Royal Society of Medicine https://journals.sagepub.com/toc/jrsa/26/2 Fleming BMJ 1941 correspondence https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2162878/pdf/brmedj04059-0024a.pdf Did Fleming deserve the Nobel? https://link.springer.com/content/pdf/10.1007/s11948-019-00149-5.pdf Beta-lactam pharmcology https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369031/ https://www.ncbi.nlm.nih.gov/books/NBK554560/ https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/beta-lactam-antibiotic https://pubs.acs.org/doi/10.1021/ja038445l https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144564/ Florey and Chain biography https://sciencehistory.org/education/scientific-biographies/howard-walter-florey-and-ernst-boris-chain/ https://www.pbs.org/newshour/health/the-real-story-behind-the-worlds-first-antibiotic Ramon y Cajal biography https://history.nih.gov/pages/viewpage.action?pageId=1016727 Florey letters https://royalsocietypublishing.org/doi/pdf/10.1098/rsbm.1971.0011 Republication of 1940 Penicillin as Chemotherapeutic Agent https://journals.lww.com/clinorthop/fulltext/2005/10000/the_classic__penicillin_as_a_chemotherapeutic.7.aspx Howard Florey and the Development of Penicillin https://www.jstor.org/stable/pdf/532209 History of Corn! https://www.washingtonpost.com/news/wonk/wp/2012/08/16/a-brief-history-of-u-s-corn-in-one-chart/ Anne Miller and the New Haven hospital https://medicine.yale.edu/news/yale-medicine-magazine/article/fulton-penicillin-and-chance/ https://www.nytimes.com/1999/06/09/us/anne-miller-90-first-patient-who-was-saved-by-penicillin.html Younkin’s economic model (2008) https://irle.berkeley.edu/culture/papers/Younkin-Mar08.pdf 💻 C O N T A C T 💻 If you’d like to sponsor a video or have other business inquiries: patkellyteaches [at] gmail.com ⌛T I M E S T A M P S ⌛ 0:00 intro 0:37 Alexander Fleming and St. Mary’s4 4:27 Penicillin pharmacology 8:37 The Oxford Crew 12:44 1939 Mouse Experiment 16:14 Penicillin Production 24:47 The Economics of Penicillin 27:37 The Problems with Penicillin #historyofmedicine #medicalhistory
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