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| Name | Slurred Speech in Germ Cell Tumor Encephalitis |
| Video Uploader | Video From JAMA Network |
| Upload Date | This Video Uploaded At 03-08-2020 15:00:03 |
| Video Discription | Patients with germ cell tumors may develop paraneoplastic encephalitis, and immunoglobulin G autoantibodies to Kelch-like protein 11 (KLHL11) have been identified as a biomarker. This video demonstrates dysarthria in a patient with autoimmune KLHL11 encephalitis, which may also include ataxia, diplopia, nystagmus, hearing loss, tinnitus, and vertigo. Click https://youtu.be/hb9m-nK2cVg for demonstration of ataxia, https://youtu.be/GPqg1sk4Jv0 for illustration of nystagmus in the same patient, and https://ja.ma/3hx6aUH for full clinical details from a case series of patients with testicular cancer-related KLHL11 encephalitis. |
| Category | Science & Technology |
| Tags | GCT | Germ Cell Tumor | Seminoma | Testicular Cancer | Paraneoplastic | Encephalitis | Autoantibodies | Urology | Autoimmune | Autoimmunity | Neurology | Neuroophthalmology | Oncology | Neuro-oncology | Medicine |
